Expression of Timp1 in mouse tooth

tissue inhibitor of metalloproteinase 1; Clgi; EPA; erythroid potentiating activity; HCI; collagenase inhibitor, human

Species: mouse
Location in mouse genome: chromosome X, 19424257 - 19427851 (UCSC, assembly October 2003)
Tooth: lower molar and incisor
Method: in situ hybridization (radioactive), probe:


Initiation stage
No expression: oral epithelium, dental epithelium, dental mesenchyme

Bud stage
Expression: dental mesenchyme
No expression: oral epithelium, dental epithelium

Cap stage
Expression: dental papilla
No expression: oral epithelium, outer enamel epithelium, inner enamel epithelium, enamel knot, stellate reticulum, dental sac

Bell stage
No expression: oral epithelium, outer enamel epithelium, inner enamel epithelium, stratum intermedia, stellate reticulum, dental papilla, dental sac

Late bell
(differentiation) stage
Expression: preodontoblasts
No expression: outer enamel epithelium, stratum intermedia, stellate reticulum, preameloblasts, dental papilla, dental sac

Secretory stage
Expression: odontoblasts
No expression: outer enamel epithelium, stratum intermedia, stellate reticulum, ameloblasts, dental papilla, dental sac

Root development
Expression: odontoblasts
No expression: dental papilla, cementoblasts, periodontal ligament


Source references:
Sahlberg,C., Reponen,P., Tryggvason,K., and, Thesleff,I. (1999) European Journal of Oral Sciences 107(2):121-130
Yoshiba,N., Yoshiba,K., Stoetzel,C., Perrin-Schmitt,F., Cam,Y., Ruch,J.V., and, Lesot,H. (2003) Developmental Dynamics 228(1):105-112

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Data last edited 30.08.1999 by M.P., page last created 10.12.2004 by P.N.