| Transgenic mice deficient in both prx1 and prx2 lack mandibular incisors. The development is arrested within bud stage as a single incisor bud..
|
| Prx1 has similar expression pattern as prx2 (from ED 10.5 to 12.5).
|
|
| Source references:
|
|
Lu,M.F., Cheng,H.T., Kern,M.J., Potter,S.S., Tran,B., Diekwisch,T.G.H., Martin, JF., Jmartin@ibt.tamu.edu, Paired-related homeobox, Craniofacial development, Genetic redundancy, Mouse, and, Prx-1.
(1999) Development 126(3):495-504
|
|
| Other references:
|
|
ten Berge,D., Brouwer,A., Korving,J., Martin,J.F., Meijlink,F., frits@niob.knaw.nl, Mouse, Homeobox gene, Gene targeting, Aristaless domain, Epitheliomesenchymal interaction, Craniofacial development, Limb, Inner, and, ear.
(1998) Development 125(19):3831-3842
|