Expression of Notch3 in mouse tooth

Species: mouse
Location in mouse genome: chromosome 17, 31775805 - 31821744 (UCSC, assembly October 2003)
Tooth: lower molar
Method: in situ hybridization (radioactive), probe:


Initiation stage
Expression: dental epithelium
No expression: oral epithelium, dental mesenchyme

Bud stage
Expression: dental epithelium
No expression: oral epithelium, dental mesenchyme

Discrepancy between reports..

Cap stage
No expression: oral epithelium, outer enamel epithelium, inner enamel epithelium, enamel knot, stellate reticulum, dental papilla, dental sac

Bell stage
Expression: stratum intermedia, dental papilla
No expression: oral epithelium, outer enamel epithelium, inner enamel epithelium, stellate reticulum, dental sac

Late bell
(differentiation) stage
Expression: stratum intermedia, dental papilla
No expression: outer enamel epithelium, stellate reticulum, preameloblasts, dental sac, preodontoblasts

Secretory stage
Expression: stratum intermedia, dental papilla, dental sac
No expression: outer enamel epithelium, stellate reticulum, ameloblasts, odontoblasts


Source references:
Mitsiadis,T.A., Lardelli,M., Lendahl,U., and, Thesleff,I. (1995) Journal of Cell Biology 130(2):407-418

Other references:
Mustonen,T., Tummers,M., Mikami,T., Itoh,N., Zhang,N., Gridley,T., and, Thesleff,I. (2002) Developmental Biology 248(2):281-293

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Data last edited 10.12.2004 by M.K., page last created 10.12.2004 by P.N.