Expression of midkine in mouse tooth

Mdk; neurite growth promoting factor 2 (Negf2); MK

Species: mouse
Tooth: molar
Method: in situ hybridization (radioactive), probe:


Initiation stage
Expression: oral epithelium, dental mesenchyme
No expression: dental epithelium

Bud stage
Expression: dental epithelium, dental mesenchyme
No expression: oral epithelium

Cap stage
Expression: outer enamel epithelium, inner enamel epithelium, dental papilla, dental sac
No expression: oral epithelium, enamel knot, stellate reticulum

Bell stage
Expression: outer enamel epithelium, inner enamel epithelium, dental papilla, dental sac
No expression: oral epithelium, stratum intermedia, stellate reticulum

Late bell
(differentiation) stage
Expression: stratum intermedia, preameloblasts, dental papilla, preodontoblasts
No expression: outer enamel epithelium, stellate reticulum, dental sac


Source references:
Mitsiadis,T.A., Muramatsu,T., Muramatsu,H., and, Thesleff,I. (1995) Journal of Cell Biology 129(1):267-281

Other references:
Mitsiadis,T.A., Salmivirta,M., Muramatsu,T., Muramatsu,H., Rauvala,H., Lehtonen,E., Jalkanen,M., and, Thesleff,I. (1995) Development 121(1):37-51

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Data last edited 05.04.2004 by M.K., page last created 10.12.2004 by P.N.