Expression of laminin 5 gamma 2 in mouse tooth

Lamc2; kalinin, nicein, epiligrin; Lamb2, truncated (Lamb2T)

Species: mouse
Tooth: molar
Method: immunochemistry, antibody: affinity purified polyclonal


Initiation stage
Expression: oral epithelium, basement membrane
No expression: dental epithelium, dental mesenchyme

Bud stage
Expression: oral epithelium, dental epithelium, basement membrane
No expression: dental mesenchyme

Cap stage
Expression: oral epithelium, outer enamel epithelium, inner enamel epithelium, stellate reticulum, basement membrane
No expression: enamel knot, dental papilla, dental sac

Bell stage
Expression: oral epithelium, outer enamel epithelium, inner enamel epithelium, basement membrane
No expression: stratum intermedia, stellate reticulum, dental papilla, dental sac

Absent from basement membrane associated with the inner enamel epithelium. Weak still in regions of cervical loop and decreased towards the cervical loop..

Late bell
(differentiation) stage
Expression: preameloblasts
No expression: outer enamel epithelium, stratum intermedia, stellate reticulum, basement membrane, dental papilla, dental sac, preodontoblasts

Secretory stage
Expression: ameloblasts, enamel
No expression: outer enamel epithelium, stratum intermedia, stellate reticulum, dental papilla, dental sac, odontoblasts, predentin, dentin


Source references:
Yoshiba,K., Yoshiba,N., Aberdam,D., Meneguzzi,G., Perrin-Schmitt,F., Stoetzel,C., Ruch,J.V., and, Lesot,H. (1998) Developmental Dynamics 211(2):164-176

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Data last edited 14.11.2001 by M.P., page last created 10.12.2004 by P.N.