Expression of laminin alpha 1 in mouse tooth

Lama1; laminin A

Species: mouse
Tooth: molar
Method: in situ hybridization (radioactive), probe:


Bud stage
Expression: dental mesenchyme
No expression: oral epithelium, dental epithelium

Expression was detected by immunohistochemistry only in E13 after 7 days organ culture. The staining was in the dental papilla and the dental basement membrane..

Cap stage
Expression: dental papilla, dental sac
No expression: oral epithelium, outer enamel epithelium, inner enamel epithelium, enamel knot, stellate reticulum

Bell stage
Expression: dental papilla, dental sac
No expression: oral epithelium, outer enamel epithelium, inner enamel epithelium, stratum intermedia, stellate reticulum

Late bell
(differentiation) stage
Expression: dental papilla, dental sac
No expression: outer enamel epithelium, stratum intermedia, stellate reticulum, preameloblasts, preodontoblasts

Secretory stage
Expression: odontoblasts
No expression: outer enamel epithelium, stratum intermedia, stellate reticulum, ameloblasts, dental papilla, dental sac

Expression was localized to polarized odontoblasts and lost from secreting odontoblasts.


Source references:
Salmivirta,K., Sorokin,L., and, Ekblom,P. (1997) Developmental Dynamics 210(3):206-215

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Data last edited 03.12.1997 by M.P., page last created 10.12.2004 by P.N.