Expression of IKKA in mouse tooth |
| Chuk; IkappaB kinase alpha; IKK-alpha; IKK1 |
| Species: mouse |
| Tooth: molar |
| Method: in situ hybridization (radioactive), probe: |
Bud stage | |
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Expression: oral epithelium, dental epithelium No expression: dental mesenchyme |
Cap stage | |
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Expression: oral epithelium, outer enamel epithelium, inner enamel epithelium, dental papilla No expression: enamel knot, stellate reticulum, dental sac |
| Sonic hedgehog expression region is larger in presuumptive incisor epithelium in IKKA null mutant mouse. (Ohazama et al 2004) See expression of Sonic hedgehog. |
| Notch1 expression is downregulated in incisor and molar epithelium of IKKA -/- mouse. (Ohazama et al 2004) See expression of Notch1. |
| Region that is negative for Wnt7b expression region is larger in presumptive incisor epithelium in IKKA null mutant mouse. (Ohazama et al 2004) See expression of Wnt7b. |
| Notch2 expression is downregulated in incisor but not in molar epithelium of IKKA -/- mouse. (Ohazama et al 2004) See expression of Notch2. |
| Weak expression was detected at E11.5 and E12.5 in presumptive incisor epithelium. |
| Source references: |
| Ohazama,A., Hu,Y., Schmidt-Ullrich,R., Cao,Y., Scheidereit,C., Karin,M., and, Sharpe,P.T. (2004) Dev Cell 6(2):219-227 |