Expression of follistatin in rat tooth


Species: rat
Location in rat genome: chromosome 2, 46470478 - 46478911 (UCSC, assembly June 2003)
Method: in situ hybridization (radioactive), probe:

Cap stage
Expression: oral epithelium, outer enamel epithelium, inner enamel epithelium
No expression: enamel knot, stellate reticulum, dental papilla, dental sac

Partial failure in tooth development in transgenic mice deficient in follistatin (Matzuk et al., 1995).

Source references:
Roberts,V.J., and, Barth,S.L. (1994) Endocrinology 134(2):914-923

Other references:
Matzuk,M.M., Lu,N., Vogel,H., Sellheyer,K., Roop,D.R., Bradley, and, A. (1995) Nature 374(6520):360-363

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Data last edited 07.10.1996 by M.P., page last created 10.12.2004 by P.N.