Expression of activin beta A in mouse tooth | ||||
Inhba; Inhba; inhibin/activin beta A; inhibin/activin betaA; follicle-stimulating hormone-releasing protein; follicle-stimulating hormone releasing protein; Frp; Frp; FSH releasing protein; FSH-releasing protein; FSH releasi
| Species: mouse
| Location in mouse genome: chromosome X, 96048655 - 96065874 (UCSC, assembly October 2003)
| Tooth: molar
| Method: in situ hybridization (radioactive), probe: 381 nt
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Initiation stage | |
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Expression: dental mesenchyme No expression: oral epithelium, dental epithelium |
Bud stage | |
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Expression: dental mesenchyme No expression: oral epithelium, dental epithelium |
Cap stage | |
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Expression: dental papilla No expression: oral epithelium, outer enamel epithelium, inner enamel epithelium, enamel knot, stellate reticulum |
Bell stage | |
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Expression: dental papilla, dental sac No expression: oral epithelium, outer enamel epithelium, inner enamel epithelium, stratum intermedia, stellate reticulum |
Late bell (differentiation) stage | |
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No expression: outer enamel epithelium, stratum intermedia, stellate reticulum, preameloblasts, dental papilla, dental sac, preodontoblasts | |
Secretory stage | |
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No expression: outer enamel epithelium, stratum intermedia, stellate reticulum, ameloblasts, dental papilla, dental sac, odontoblasts | |
| Activin (in beads) induced EDAR expression in epithelium. (Laurikkala et al 2001) See expression of Edar. |
| Partial failure in tooth development in transgenic mice deficient in Activin beta A. |
| Source references: |
| Ferguson,C.A., Tucker,A.S., Christensen,L., Lau,A.L., Matzuk,M.M., and, Sharpe,P.T. (1998) Genes & Development 12(16):2636-2649 |
| Heikinheimo,K., Bègue-Kirn,C., Ritvos,O., Tuuri,T., and, Ruch,J.V. (1997) Journal of Dental Research 76(10):1625-1636 |
| Other references: |
| Åberg,T., Wang,X.P., Kim,J.H., Yamashiro,T., Bei,M., Rice,R., Ryoo,H.M., and, Thesleff,I. (2004) Developmental Biology 270(1):76-93 |