Expression of Msx2 in vole tooth

Hox8; expression in diastema buds
; Msh (muscle segment homeobox) drosophila homolog 2

Species: vole
Tooth: molar
Method: in situ hybridization (radioactive), probe: 800nt


Bud stage
Expression: dental epithelium, dental mesenchyme
No expression: oral epithelium

Buccal bias..

Cap stage
Expression: enamel knot, stellate reticulum, dental papilla
No expression: oral epithelium, outer enamel epithelium, inner enamel epithelium

Bell stage
Expression: inner enamel epithelium, stratum intermedia, stellate reticulum, dental papilla
No expression: oral epithelium, outer enamel epithelium, dental sac

In Msx1/Msx2 double knockout mice, tooth development is arrested either during the initiation stage or early bud stages.

Source references:
Keränen,S.V.E., Åberg,T., Kettunen,P., Thesleff,I., and, Jernvall,J. (1998) Development Genes & Evolution 208(9):477-486

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Data last edited 24.08.1998 by M.P., page last created 10.12.2004 by P.N.