Expression of Timp3 in mouse tooth

tissue inhibitor of metalloproteinase 3

Species: mouse
Location in mouse genome: chromosome 10, 88700332 - 88749302 (UCSC, assembly October 2003)
Tooth: lower molar
Method: in situ hybridization (radioactive), probe:


Bud stage
Expression: oral epithelium, dental epithelium
No expression: dental mesenchyme

Cap stage
Expression: oral epithelium, outer enamel epithelium
No expression: inner enamel epithelium, enamel knot, stellate reticulum, dental papilla, dental sac

Bell stage
Expression: oral epithelium, outer enamel epithelium, dental papilla
No expression: inner enamel epithelium, stratum intermedia, stellate reticulum, dental sac

Late bell (differentiation) stage
Expression: stratum intermedia, preameloblasts

Expression remained in the subodontoblast layer..


Source references:
Yoshiba,N., Yoshiba,K., Stoetzel,C., Perrin-Schmitt,F., Cam,Y., Ruch,J.V., and, Lesot,H. (2003) Developmental Dynamics 228(1):105-112

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Data last edited 11.12.2003 by M.K., page last created 10.12.2004 by P.N.