Expression of Timp2 in mouse tooth

tissue inhibitor of metalloproteinase 2

Species: mouse
Location in mouse genome: chromosome 11, 117853974 - 117908218 (UCSC, assembly October 2003)
Tooth: molar
Method: in situ hybridization (radioactive), probe:


Bud stage
Expression: dental mesenchyme
No expression: oral epithelium, dental epithelium

Cap stage
Expression: dental papilla, dental sac
No expression: oral epithelium, outer enamel epithelium, inner enamel epithelium, enamel knot, stellate reticulum

Bell stage
Expression: dental papilla, dental sac
No expression: stellate reticulum

Late bell (differentiation) stage
Expression: preameloblasts, dental sac, preodontoblasts
No expression: stellate reticulum, dental papilla

Secretory stage
Expression: stellate reticulum, dental papilla, odontoblasts
No expression: outer enamel epithelium, stratum intermedia, ameloblasts, dental sac

Day 2 postnatally in stellate reticulum a very faint expression might be seen..


Source references:
Sahlberg,C., Reponen,P., Tryggvason,K., and, Thesleff,I. (1999) European Journal of Oral Sciences 107(2):121-130
Yoshiba,N., Yoshiba,K., Stoetzel,C., Perrin-Schmitt,F., Cam,Y., Ruch,J.V., and, Lesot,H. (2003) Developmental Dynamics 228(1):105-112


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Data last edited 09.09.1999 by M.P., page last created 10.12.2004 by P.N.