Expression of Tgfb1 in mouse tooth

transforming growth factor beta 1; Tgf beta-1

Species: mouse
Tooth: lower molar
Method: in situ hybridization (radioactive), probe:


Initiation stage
No expression: oral epithelium, dental epithelium, dental mesenchyme

Bud stage
Expression: dental epithelium, dental mesenchyme
No expression: oral epithelium

Cap stage
Expression: inner enamel epithelium, enamel knot, stellate reticulum, dental papilla
No expression: oral epithelium, outer enamel epithelium, dental sac

Bell stage
Expression: inner enamel epithelium
No expression: oral epithelium, outer enamel epithelium, stratum intermedia, stellate reticulum, dental papilla, dental sac

Late bell
(differentiation) stage
Expression: preodontoblasts
No expression: outer enamel epithelium, stratum intermedia, stellate reticulum, preameloblasts, dental papilla, dental sac

Discrepancy between reports. In 19-day embryos, the stratum intermedium cells transiently expressed Tgfbeta1 RNA..

Secretory stage
Expression: ameloblasts, odontoblasts
No expression: outer enamel epithelium, stratum intermedia, stellate reticulum, dental papilla, dental sac


Source references:
Vaahtokari,A., Vainio,S., and, Thesleff,I. (1991) Development 113(3):985-994

Other references:
Åberg,T., Wang,X.P., Kim,J.H., Yamashiro,T., Bei,M., Rice,R., Ryoo,H.M., and, Thesleff,I. (2004) Developmental Biology 270(1):76-93


To the top of the page Titlepage mouse, protein Send your comments
Pubmed Genbank Jackson Mouse Genome Database Transgene Database OMIM Kidney Base

Data last edited 26.04.2004 by M.K., page last created 10.12.2004 by P.N.