Dollé,P., Price,M., and, Duboule,D.
Expression of the murine Dlx-1 homeobox gene during facial, ocular and limb development.
Differentiation 49(2):93-99 (1992).
We have analysed the expression pattern of the mouse homeobox containing gene Dlx-1. This gene harbors a homeodomain related to that found in the Drosophila distal-less (dll) gene. In addition to its expression in the developing forebrain, Dlx-1 is transcribed in several structures containing cells of neural crest origin such as the facial mesenchyme and various elements of the peripheral nervous system. Dlx-1 transcripts are also detected in the differentiating retina and during limb morphogenesis, in the apical ectodermal ridge. The possible involvement of Dlx-1 during facial, ocular and limb development is discussed.
Last edited 10.12.2004 by P.N.