Expression of Lhx6 in mouse tooth

Lim homeobox protein 6; Lhx6.1

Species: mouse
Location in mouse genome: chromosome 2, 36356509 - 36378239 (UCSC, assembly October 2003)
Method: in situ hybridization (radioactive), probe:


Initiation stage
Expression: dental mesenchyme
No expression: oral epithelium, dental epithelium

Bud stage
Expression: dental mesenchyme
No expression: oral epithelium, dental epithelium

Cap stage
Expression: dental papilla, dental sac
No expression: oral epithelium, outer enamel epithelium, inner enamel epithelium, enamel knot, stellate reticulum

Bell stage
Expression: dental papilla
No expression: oral epithelium, outer enamel epithelium, inner enamel epithelium, stratum intermedia, stellate reticulum

Late bell (differentiation) stage
Expression: dental papilla
No expression: outer enamel epithelium, stratum intermedia, stellate reticulum, preameloblasts, preodontoblasts

Secretory stage
No expression: outer enamel epithelium, stratum intermedia, stellate reticulum, ameloblasts, dental papilla, dental sac, odontoblasts

Expression downregulated by postnatal day 2..


Source references:
Grigoriou,M., Tucker,A.S., Sharpe,P.T., and, Pachnis,V. (1998) Development 125(11):2063-2074

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Data last edited 05.04.2004 by M.K., page last created 10.12.2004 by P.N.