Expression of Lfng in mouse tooth

Lfng; lunatic fringe

Species: mouse
Tooth: molar
Method: in situ hybridization (radioactive), probe:


Initiation stage
No expression: oral epithelium, dental epithelium, dental mesenchyme

Discrepancy between reports..

Bud stage
No expression: oral epithelium, dental epithelium, dental mesenchyme

Cap stage
Expression: outer enamel epithelium, inner enamel epithelium, stellate reticulum
No expression: oral epithelium, enamel knot, dental papilla, dental sac

Secretory stage
Expression: outer enamel epithelium
No expression: stratum intermedia, stellate reticulum, ameloblasts, dental papilla, dental sac, odontoblasts

Expression was in the cervical loop area, in Hertwig's epithelial root sheat..


Source references:
Mustonen,T., Tummers,M., Mikami,T., Itoh,N., Zhang,N., Gridley,T., and, Thesleff,I. (2002) Developmental Biology 248(2):281-293
Tummers,M., and, Thesleff,I. (2003) Development 130(6):1049-1057

Other references:
Pouyet,L., and, Mitsiadis,T.A. (2000) Mech Dev JID - 9101218 91(1-2):399-402

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Data last edited 09.12.2004 by M.K., page last created 10.12.2004 by P.N.