Expression of Lef1 in mouse tooth

lymphoid enhancer binding factor 1; transcription factor, T-cell specific, 1 alpha; Tcf1 alpha

Location in mouse genome: chromosome 3, 134712216 - 134824914 (UCSC, assembly October 2003)

Method: in situ hybridization (radioactive), probe: 360b

Initiation stage
	*Expression:* dental epithelium, dental mesenchyme *No expression:* oral epithelium
Bud stage
	*Expression:* dental epithelium, dental mesenchyme *No expression:* oral epithelium
Cap stage
	*Expression:* outer enamel epithelium, inner enamel epithelium, enamel knot, dental papilla *No expression:* oral epithelium, stellate reticulum, dental sac Protein distribution similar at cap stage.. Shh expression is lost in the enamel knot in the Lef1 null mutant mouse (Kratochwil et al 2002). See expression of Sonic hedgehog. Bmp2 expression is lost in the enamel knot in the Lef1 null mutant mouse (Kratochwil et al 2002). See expression of Bmp2. Bmp4 expression is lost in the enamel knot in the Lef1 null mutant mouse (Kratochwil et al 2002). See expression of Bmp4. Bmp7 expression is lost in the enamel knot in the Lef1 null mutant mouse (Kratochwil et al 2002). See expression of Bmp7. Fgf4 expression is lost in the enamel knot in the Lef1 null mutant mouse (Kratochwil et al 2002). See expression of Fgf4. Fgf4 expression is a direct target of and positively regulated by Lef1 (Kratochwil et al 2002). See expression of Fgf4. Fgf9 expression is lost in dental epithelium in the Lef1 null mutant mouse (Kratochwil et al 2002). See expression of Fgf9. Fgf3 expression is lost in the enamel knot and dental mesenchyme in the Lef1 null mutant mouse (Kratochwil et al 2002). See expression of Fgf3. Fgf10 expression is lost in dental mesenchyme in the Lef1 null mutant mouse (Kratochwil et al 2002). See expression of Fgf10.