Expression of Lef1 in mouse tooth |
| Lef1; lymphoid enhancer binding factor 1; transcription factor, T-cell specific, 1 alpha (Tcf1 alpha) |
| Species: mouse |
| Location in mouse genome: chromosome 3, 134712216 - 134824914 (UCSC, assembly October 2003) |
| Tooth: diastema bud |
| Method: in situ hybridization (radioactive), probe: murine 660b |
Initiation stage | |
|
Expression: oral epithelium, dental epithelium, dental mesenchyme | |
Bud stage | |
|
Expression: oral epithelium, dental epithelium, dental mesenchyme | |
| Mouse null mutants of Lef1 do not develop teeth. |
| Lef1expression in the enamel knot is necessary for tooth development. |
| Source references: |
| Keränen,S.V.E., Kettunen,P., Åberg,T., Thesleff,I., and, Jernvall,J. (1999) Development Genes & Evolution 209(8):495-506 |
| To the top of the page | Titlepage | mouse, mRNA | vole, mRNA | vole, mRNA | Send your comments |
| Pubmed | Genbank | Jackson Mouse Genome Database | OMIM |