Expression of Dlx3 in mouse tooth

Dlx3; distal-less homeobox 3

Species: mouse
Location in mouse genome: chromosome 11, 94703748 - 94708897 (UCSC, assembly October 2003)
Tooth: molar and incisor
Method: in situ hybridization (radioactive), probe: 1,1kb


Initiation stage
No expression: oral epithelium, dental epithelium, dental mesenchyme

Bud stage
Expression: dental mesenchyme
No expression: oral epithelium, dental epithelium

Epithelium positive in incisor bud..

Cap stage
Expression: dental papilla
No expression: oral epithelium, outer enamel epithelium, inner enamel epithelium, enamel knot, stellate reticulum, dental sac

Bell stage
Expression: inner enamel epithelium, dental papilla
No expression: oral epithelium, outer enamel epithelium, stratum intermedia, stellate reticulum, dental sac

Late bell (differentiation) stage
Expression: preameloblasts, dental papilla, preodontoblasts
No expression: outer enamel epithelium, stratum intermedia, stellate reticulum, dental sac

Drosophila relative: distalless.
Mutations in DLX3 cause trichodentoosseous syndrome.

Source references:
Robinson,G.W., and, Mahon,K.A. (1994) Mechanisms of Development 48(3):199-215

Other references:
Weiss,K.M., Bollekens,J., Ruddle,F.H., and, Takashita,K. (1994) Journal of Experimental Zoology 270(3):273-284
Zhao,Z.Y., Stock,D.W., Buchanan,A.V., and, Weiss,K.M. (2000) Development Genes & Evolution 210(5):270-275

To the top of the page Titlepage Send your comments
Pubmed Genbank Jackson Mouse Genome Database Transgene Database OMIM transfac

Data last edited 07.10.1996 by M.P., page last created 10.12.2004 by P.N.