Expression of Dlx1 in mouse tooth |
| Dlx1; distal-less homeobox 1 |
| Species: mouse |
| Location in mouse genome: chromosome 2, 71870700 - 71875236 (UCSC, assembly October 2003) |
| Tooth: molar |
| Method: in situ hybridization (radioactive), probe: 100b,900b |
Bud stage | |
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Expression: dental mesenchyme No expression: oral epithelium, dental epithelium |
Cap stage | |
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Expression: dental papilla, dental sac No expression: oral epithelium, outer enamel epithelium, inner enamel epithelium, enamel knot, stellate reticulum |
| Transgenic mice lacking both Dlx1 and Dlx2 genes do not develop maxillary molars. The development is arrested after initiation.. |
| Drosophila relative: distalless. |
| Source references: |
| Dollé,P., Price,M., and, Duboule,D. (1992) Differentiation 49(2):93-99 |
| Other references: |
| Bei,M., and, Maas,R. (1998) Development 125(21):4325-4333 |
| Zhao,G.Q., Zhao,S., Zhou,X., Eberspaecher,H., Solursh,M., and, de Crombrugghe,B. (1994) Developmental Biology 164(1):37-51 |
| Zhao,Z.Y., Stock,D.W., Buchanan,A.V., and, Weiss,K.M. (2000) Development Genes & Evolution 210(5):270-275 |