Expression of Met proto-oncogene in mouse tooth

Met; hepatocyte growth factor receptor (Hgfr); met-receptor; oncogene met; renal cell carcinoma, papillary, 2 gene (Rccp2)

Species: mouse
Tooth: molar
Method: in situ hybridization (radioactive), probe: 471b


Cap stage
Expression: outer enamel epithelium
No expression: oral epithelium, inner enamel epithelium, enamel knot, stellate reticulum, dental papilla, dental sac

Bell stage
Expression: outer enamel epithelium, inner enamel epithelium
No expression: oral epithelium, stratum intermedia, stellate reticulum, dental papilla, dental sac

Late bell
(differentiation) stage
Expression: outer enamel epithelium, stellate reticulum, preameloblasts
No expression: stratum intermedia, dental papilla, dental sac, preodontoblasts

C-met is receptor for HGF.

Source references:
Sonnenberg,E., Meyer,D., Weidner,K.M., and, Birchmeier,C. (1993) Journal of Cell Biology 123(1):223-235

Other references:
Tabata,M.J., Kim,K., Yamashita,K., Matsumura,T., Kato,J., Iwamoto,M., Walkisaka,S., Matsumoto,K., Nakamura,T., Kumegawa,M., and, Kurisu,K. (1996) Development 122:1243-1251

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Data last edited 05.04.2004 by M.K., page last created 10.12.2004 by P.N.