Expression of amelogenin in mouse tooth

Amelx; Algn; Amg; Amgl

Species: mouse
Location in mouse genome: chromosome X, 157310884 - 157318072 (UCSC, assembly October 2003)
Tooth: molar
Method: in situ hybridization (radioactive), probe: 772b


Bell stage
No expression: oral epithelium, outer enamel epithelium, inner enamel epithelium, stratum intermedia, stellate reticulum, dental papilla, dental sac

Late bell (differentiation) stage
No expression: outer enamel epithelium, stratum intermedia, stellate reticulum, preameloblasts, dental papilla, dental sac, preodontoblasts

Secretory stage
Expression: ameloblasts
No expression: outer enamel epithelium, stratum intermedia, stellate reticulum, dental papilla, dental sac, odontoblasts

Root development
No expression: dental papilla, odontoblasts, cementoblasts, periodontal ligament

Mutations in amelogenin gene cause X-linked amelogenesis imperfecta..

Source references:
Snead,M.L., Luo,W., Lau,E.C., and, Slavkin,H.C. (1988) Development 104(1):77-85
Hu,J.C.C., Sun,X.L., Zhang,C.H., and, Simmer,J.P. (2001) European Journal of Oral Sciences 109(2):125-132

Other references:
Lagerström,M., Dahl,N., Nakahori,Y., Nakagome,Y., Bäckman,B., Landegren,U., and, Pettersson,U. (1991) Genomics 10(4):971-975


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Data last edited 13.04.2002 by M.P., page last created 10.12.2004 by P.N.