Expression of activin beta A in mouse tooth

Inhba; inhibin/activin betaA; follicle-stimulating hormone-releasing protein; Frp; FSH-releasing protein; FSH-releasing factor; Erythroid differentiation factor; Edf

Species: mouse
Location in mouse genome: chromosome 13, 15832716 - 15845917 (UCSC, assembly October 2003)
Tooth: molar
Method: immunochemistry, antibody: monoclonal


Bud stage
Expression: oral epithelium, dental epithelium
No expression: basement membrane, dental mesenchyme

Cap stage
Expression: oral epithelium

Observed faintly in epithelial cells of the tooth germ..

Bell stage
Expression: dental papilla
No expression: oral epithelium, outer enamel epithelium, inner enamel epithelium, stratum intermedia, stellate reticulum, basement membrane, dental sac

Observed in the tips of cusps..

Late bell (differentiation) stage: no expression

Partial failure in tooth development in transgenic mice deficient in Activin beta A.

Source references:
Heikinheimo,K., Bgue-Kirn,C., Ritvos,O., Tuuri,T., and, Ruch,J.V. (1997) Journal of Dental Research 76(10):1625-1636


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Data last edited 24.03.2004 by M.K., page last created 10.12.2004 by P.N.